Ayelén Rapoport

• Evaluation of economic and technical feasibility 12 clinical protocols. Negotiation of budgets and contracts. Evaluation of clinical protocols with respect to the center's capabilities and the amounts required for their development, patient recruitment and adherence.

Manager, Technology Liaison and Technology Transfer in Health, Agriculture and Biotechnology.

Coordination in technology transfer with a 20% increase in the approval of R&D agreements; Responsible for Negotiation and Licensing:

• 16 technology licenses negotiated and processed
• 24 Research and Development agreements
• 6 technological assistance
• Evaluation and approval of 124 High Level Technological Services.

Responsible for management and strategies for the generation of technology-based companies and Start ups.

• 15 advised technology-based companies and Start ups, including Galtec, Dharma, Apolo, Mesenchimall, Oncoliq, Oncoprecision, Libera, Hz4 Liver, New Organs.

Responsible for planning and managing the supply of technologies with high industrial value in health:

• Method of combined treatment of Spinal Muscular Atrophy Spinraza Valproic
• Micro RNAs for the treatment of diseases associated with neurodegenerative Tau protein.
• Oral vaccination platform Cysteine-rich proteins.
• Soybean for high density planting by inhibition of the Shade Avoidance system.
• Waterlogging tolerant crops associated with Homeobox from sunflower.
• Monoclonal antibody against new therapeutic target MicA in oncology treatments.

• I carried out the processing of 6 experimental trials in contained and confined field conditions.
• Managed the registration of a biosafety greenhouse in Mar del Plata.
• Managed the regulatory compliance of the biosafety greenhouse of IAL-CONICET.
• Drafted 3 dossiers for veterinary vaccines, for dogs and cats, poultry and livestock.

• Planning, management and approval of 6 genetically edited pigs for xenotransplantation, under biotechnology regulatory standards, transferred to New Organs.
• Approval of 2 edited tomato lines for tolerance to fungal infections
• Approval of drought tolerant rice
• Approval of potato crop edited for pathogen tolerance
• Planning, management and approval of edited Cannabis cbd hypothetical product; and Shade avoidance soybean.

Biosafety and biological containment expert

• Management of COVID-19 related projects:
• 70 projects associated with detection, treatment and prevention.
• 7 projects of vaccine against Covid,
• 1 platform for monitoring the results of Covid clinical trials,
• 25 projects of detection methods, 4 projects of chaps and hospital protection elements, 3 respirators, among others.
• Management and processing of health projects associated with bronchial tracheoma and rare diseases. Treatment project for neglected diseases, in progress.

Vaccine risk assessment and vaccine trial evaluation.

Technical feasibility assessment of biotechnology projects.

Optimization of the evaluation process of regulatory dossiers, drafting of 4 regulatory standards with their respective forms.

Updating of biosafety and gene editing regulations for microorganisms.

Responsible for risk assessment, analysis and management, evaluation of 8 regulatory dossiers for commercialization.

Technical responsible for validation of molecular detection methods and biomarkers, evaluation of two methods for detection of events in grains.

Drafting of OECD guidelines.

Development of methods for identification of microorganisms of clinical relevance.

Preparation of culture media and environmental quality control, PCR and real-time PCR. Development of biomarkers in hospital infections. Microbiological control of hospital areas. Development of three methods for detection of microorganisms. Development of a method for rapid detection of KPC resistance.

• Intellectual property and genetic resources, Convention on Biological Diversity and international treaties.